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research-article
Author(s):
Gustavo Martínez-Mier ,
Miguel A. Carrasco-Arroniz ,
Ana G. De Los Santos-Lopez ,
José M. Reyes-Ruiz
Publication date (Print and electronic): June 2024
Journal: Cirugía y cirujanos
Publisher: Academia Mexicana de Cirugía A.C.
Keywords: Colorectal surgery, Anastomosis leak, Colon leakage score, Outcomes, Risk prediction, Cirugía colorrectal, Fuga de anastomosis, Puntuación de fuga de colon, Resultados, Predicción de riesgo
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Abstract Objective: The study aims to apply the CLS in patients undergoing left-sided colorectal surgery. Method: Retrospective study in patients with the left-sided colorectal surgery and primary anastomosis without diverting stoma. CLS was calculated in patients, who were classified in AL and NO-AL groups. Predictive value of CLS was evaluated by receiver operator characteristic. Correlation between CLS and AL was determined. 208 patients (55% male, mean age 59 years) were included in the study. Results: Overall, AL was 7.2%. Mean CLS of all patients was 7.2 ± 3.2 (0-17). Patients with AL had a higher CLS (11.8 ± 2.3) than NO-AL patients (6.8 ± 3) (p = 0.0001). The area under the curve for the prediction of AL by CLS was 0.898 ([CI] 0.829-0.968, p = 0.0001). A CLS of 8.5 had 93% sensitivity and 72% specificity. There was a statistically significant odds ratio for CLS and AL (0.58: [CI] 0.46-0.73, p = 0.0001). Conclusions: CLS is a useful tool to predict AL in the left-sided colorectal surgery. Resumen Objetivo: Este estudio tiene el objetivo de aplicar el CLS en pacientes con cirugía colorrectal de lado izquierdo. Método: Estudio retrospectivo en pacientes con cirugía colorrectal izquierda y anastomosis primaria sin estoma de derivación. Se calculó el CLS en los pacientes, los cuales fueron clasificados en los grupos con AL y sin AL. Resultados: La media del CLS de todos los pacientes fue de 7.2 ± 3.2 (0-17). Los pacientes con AL tenían un CLS más alto (11.8 ± 2.3) que los pacientes sin AL (6.8 ± 3) (p = 0.0001). El área bajo la curva para la predicción de la AL mediante el CLS fue de 0.898 (intervalo de confianza (CI) 0.829-0.968; p = 0.0001). Un CLS de 8.5 tuvo una sensibilidad del 93% y una especificidad del 72%. Además, se obtuvo un Odds Ratio con una diferencia estadísticamente significativa para el CLS y AL (0.58; CI 0.46-0.73; p = 0.0001). Conclusiones: La CLS es una herramienta útil para predecir la AL en la cirugía colorrectal del lado izquierdo. Abstract
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Most cited references21
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Systematic review of preoperative, intraoperative and postoperative risk factors for colorectal anastomotic leaks.
F McDermott, P Heeney, M Kelly … (2015)
Anastomotic leak (AL) represents a dreaded complication following colorectal surgery, with a prevalence of 1-19 per cent. There remains a lack of consensus regarding factors that may predispose to AL and the relative risks associated with them. The objective was to perform a systematic review of the literature, focusing on the role of preoperative, intraoperative and postoperative factors in the development of colorectal ALs.
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Systematic review and meta-analysis of the role of defunctioning stoma in low rectal cancer surgery.
Norbert Hüser, Christoph W Michalski, Mert Erkan … (2008)
The role of a defunctioning stoma in patients undergoing low anterior resection for rectal cancer is still the subject of controversy. Recent studies suggest reduced morbidity after low anterior rectal resection with a defunctioning stoma. Retrospective and prospective studies published between 1966 and 2007 were systematically reviewed. Randomized controlled trials (RCTs) comparing anterior resections with or without defunctioning stoma were included in a meta-analysis. The pooled estimates of clinically relevant anastomotic leakages and of reoperations were analyzed using a random effects model (odds ratio and 95% confidence interval, CI). Relevant retrospective single (n = 18) and multicenter (n = 9) studies were identified and included in the systematic review. Analysis of incoherent data of the leakage rates in these nonrandomized studies demonstrated that a defunctioning stoma did not influence the occurrence of anastomotic failure but seemed to ameliorate the consequences of the leak. Four RCTs were included in the meta-analysis. The odds ratio for clinically relevant anastomotic leakage was 0.32 (95% CI 0.17-0.59), revealing a statistically significant benefit conferred through a defunctioning stoma (Z = 3.65, P = 0.0003). The odds ratio for reoperation because of leakage-caused complications was 0.27 (95% CI 0.14-0.51), with significantly fewer reoperations in patients with a defunctioning stoma (Z = 3.95, P < 0.0001). Overall mortality rates were comparable regardless of the presence of a defunctioning stoma. A defunctioning stoma reduces the rate of clinically relevant anastomotic leakages and is thus recommended in surgery for low rectal cancers.
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Surgeons lack predictive accuracy for anastomotic leakage in gastrointestinal surgery.
Clark J Zeebregts, A Karliczek, T Wiggers … (2009)
The dramatic clinical consequences of anastomotic leakage in gastrointestinal surgery can be reduced by a diverting stoma or drainage of the peri-anastomotic area. Currently, the surgeons' clinical judgement is of major importance in decision making, but reliable data of the diagnostic accuracy are lacking. In this prospective clinical study, the surgeons' predictive accuracy for anastomotic leakage was evaluated. In 191 patients undergoing colorectal resection with anastomosis, the risk for anastomotic leakage was determined by the surgeon on the basis of a visual analogue scale (VAS). This risk assessment was compared to the actual occurrence of anastomotic leakage post-operatively. A total of 26 (13.6%) patients showed anastomotic leakage. The surgeons' median predicted leakage rate was 7.1% in anastomoses >15 cm from the anal verge and 9.5%
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Author and article information
Journal
Journal ID (publisher-id): cicr
Title: Cirugía y cirujanos
Abbreviated Title: Cir. cir.
Publisher: Academia Mexicana de Cirugía A.C. (Ciudad de México, Ciudad de México, Mexico )
ISSN (Print): 0009-7411
ISSN (Electronic): 2444-054X
Publication date (Print and electronic): June 2024
Volume: 92
Issue: 3
Pages: 388-394
Affiliations
[1] Veracruz orgnameCentro Médico Nacional "Adolfo Ruiz Cortines," Instituto Mexicano del Seguro Social (IMSS) orgdiv1UMAE Hospital de Especialidades No. 14 orgdiv2Organ Transplantation and General Surgery Mexico
[2] Veracruz orgnameSESVER Hospital Regional de Alta Especialidad "Virgilio Uribe" 20 de Noviembre 1074 Centro orgdiv1Organ Transplantation and General Surgery Mexico
[3] Veracruz orgnameInstituto Mexicano del Seguro Social (IMSS) orgdiv1Centro Médico Nacional "Adolfo Ruiz Cortines" orgdiv2General Surgery, UMAE Hospital de Especialidades No. 14 Mexico
Article
Publisher ID: S2444-054X2024000300388 Publisher ID: S2444-054X(24)09200300388
DOI: 10.24875/ciru.22000507
SO-VID: ca8f3a11-bab7-45b4-a997-827eb432ddfc
License:
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
History
Date received : 11 October 2022
Date accepted : 15 December 2022
Page count
Figures: 0, Tables: 0, Equations: 0, References: 21, Pages: 7
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SciELO Mexico
Categories
Subject: Original articles
Keywords: Resultados,Colorectal surgery,Anastomosis leak,Colon leakage score,Outcomes,Risk prediction,Cirugía colorrectal,Fuga de anastomosis,Puntuación de fuga de colon,Predicción de riesgo
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Keywords: Resultados, Colorectal surgery, Anastomosis leak, Colon leakage score, Outcomes, Risk prediction, Cirugía colorrectal, Fuga de anastomosis, Puntuación de fuga de colon, Predicción de riesgo
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